News

Peripheral Airway Smooth Muscle but not the Trachealis is Hypercontractile in an Equine Model of Asthma.

Matusovsky, O.S. L. Kachmar, G. Ijpma, A. Benedetti, G. Bates, N. Zitouni, J.-P. Lavoie, A.-M. Lauzon, Peripheral Airway Smooth Muscle but not the Trachealis is Hypercontractile in an Equine Model of Asthma. Am. J. Respir. Cell Mol. Biol., 2015 Oct 16. [Epub ahead of print] PMID: 26473389

Nanotubes connect CD4+ T cells to airway smooth muscle cells: novel mechanism of T cell survival

Heialy, S., Zeroual, M., Farahnak, S., McGovern, T., Risse, P.-A. Novali, M., Lauzon, A.-M., Roman, H.N., and J.G. Martin, Nanotubes connect CD4+ T cells to airway smooth muscle cells: novel mechanism of T cell survival. J Immunol. 194:5626-34, 2015.

A microfluidic chamber to study the dynamics of muscle contraction

Roman, H., Juncker, D. & Lauzon, A.-M. A microfluidic chamber to study the dynamics of muscle contraction. Anal.Chem., 87, 2582–2587, 2015.

Human Trachealis and Main Bronchi Smooth Muscle Are Normo-Responsive in Asthma

IJpma, G, L. Kachmar, O. M. Matusovsky, J. H.T. Bates, J.G. Martin, A.-M. Lauzon, Human Trachealis and Main Bronchi Smooth Muscle Are Normo-Responsive in Asthma, Am J of Resp. and Crit Care Med, 191, No. 8 884-893, 2015.

Phosphate and ADP Differently Inhibit Coordinated Smooth Muscle Myosin Groups

Hilbert,L., Balassy,Z., Zitouni, N.B., Mackey, M.C. and A.-M. Lauzon. Phosphate and ADP Differently Inhibit Coordinated Smooth Muscle Myosin Groups. Biophys J., 108: 622-31; 2015.

The Role of Caldesmon and its Phosphorylation by ERK on the Binding Force of Unphosphorylated Myosin to Actin

H. N. Roman, N. B. Zitouni, L. H. Kachmar, A. Benedetti, A. Sobieszek, A.-M. Lauzon, The Role of Caldesmon and its Phosphorylation by ERK on the Binding Force of Unphosphorylated Myosin to Actin, Biophysica Biochemica Acta, 1840: 3218-3225, 2014.

CD4+ T cells enhance the contractile function of airway smooth muscle by altering the expression of MLCK and the (+) insert fast myosin isoform

Matusovsky, O.S., E. M. Nakada, L. Kachmar, E. D. Fixman, and A.- M. Lauzon. CD4+ T cells enhance the contractile function of airway smooth muscle by altering the expression of MLCK and the (+) insert fast myosin isoform. J. Physiol., 592: 2999-3012, 2014.

Molecular Mechanical Differences between Isoforms of Contractile Actin in the Presence of Isoforms of Smooth Muscle Tropomyosin

L. Hilbert, G. Bates, H.N. Roman, J. L. Blumenthal, N.B. Zitouni, A. Sobieszek, M.C. Mackey, A.-M. Lauzon. Molecular Mechanical Differences between Isoforms of Contractile Actin in the Presence of Isoforms of Smooth Muscle Tropomyosin. PLOS Computational Biology, 9(10): e1003273, 2013.

The kinetics of mechanically coupled myosins exhibit group size-dependent regimes

Hilbert, L., S. Cumarasamy, N. B. Zitouni, M. Mackey, A.-M. Lauzon. The kinetics of mechanically coupled myosins exhibit group size-dependent regimes. Biophysical Journal, 105:1466-1474, 2013.

Unphosphorylation calponin enhances the binding force of unphosphorylated myosin to actin

Roman, H. N., N.B. Zitouni, L. Kachmar, G. Ijpma, A. Benedetti, A. Sobieszek, A.-M. Lauzon. Unphosphorylated calponin enhances the binding force of unphosphorylated myosin to actin. Biophysica Biochemica Acta, 1830: 4634-4641, 2013.